Dr. Roberta Brambilla is an Associate Professor of Neurological Surgery at the Miami Project To Cure Paralysis, a center of excellence in neuroscience research of the University of Miami Miller School of Medicine. After obtaining her Ph.D. in Neuroscience from the University of Milan, Italy, she moved to the University of Miami where she trained as a post-doctoral fellow before starting her independent research lab.

Dr. Brambilla’s main interest is understanding the role of neuroinflammation in the pathophysiology of neurodegenerative disorders, such as multiple sclerosis, spinal cord injury, traumatic brain injury and stroke, with a specific focus on the contribution of glial cells. In recent years she has devoted her efforts to investigating the function of tumor necrosis factor (TNF), both membrane-bound and soluble forms, in neuroimmune disease.

Another important research topic being developed in her lab is understanding how intrinsic oligodendrocyte dysfunction might play a role in multiple sclerosis etiopathogenesis. 

More recently, she has become interested in understanding how cholesterol dysfunction may participate in the pathogenesis and progression of neurological disease, specifically multiple sclerosis and traumatic brain injury. She is studying how restoring proper cholesterol metabolism in the central nervous system may contribute to neurorepair.

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